Subtilisin
Subtilisin is a gentle enzyme used in skincare exfoliators and cleansers to help dissolve dead skin cells and leave the complexion smoother and brighter.
How it works in skincare
In cosmetics, subtilisin works as a proteolytic enzyme that selectively breaks down the proteins in the outermost layer of dead skin cells, promoting a natural shedding process without the abrasion of physical scrubs. It is often included in enzyme peels, masks and daily cleansers at low concentrations to deliver a mild resurfacing effect that supports smoother texture and improved radiance while remaining kind to the skin barrier.
Key benefits
- Gentle exfoliation of dead skin cells
- Smoother skin texture
- Brighter and more radiant complexion
- Helps unclog pores
- Softens rough or bumpy skin
- Suitable for regular use in leave-on products
Best for
dull skin, mature skin, combination skin, oily skin, rough texture
Where it comes from
Subtilisin is a naturally occurring enzyme originally derived from the fermentation of Bacillus subtilis bacteria, a process similar to that used in traditional food fermentation.
Products with Subtilisin
Not every product on UK Lips lists a full ingredient breakdown — so there may be many more formulas that contain Subtilisin than we can show here. These are the comparisons where we’ve confirmed it in the listed ingredients.