sh-Oligopeptide-78
sh-Oligopeptide-78 is a lab-made peptide used in modern skincare to support skin renewal and improve overall texture. It mimics natural signalling molecules in the skin, helping to boost collagen and elastin production for a smoother, firmer appearance. You'll often find it in targeted serums, eye creams and advanced moisturisers.
How it works in skincare
In cosmetics and skincare, sh-Oligopeptide-78 functions as a biomimetic peptide that communicates with skin cells to encourage natural repair processes. It helps stimulate the production of extracellular matrix components such as collagen, elastin and hyaluronic acid, resulting in improved firmness and elasticity. Formulators value its ability to integrate seamlessly into lightweight, water-based formulas without irritation, making it a popular choice in anti-ageing and skin-conditioning products.
Key benefits
- Helps improve skin firmness and elasticity
- Supports smoother skin texture
- Enhances skin renewal and repair
- Reduces the appearance of fine lines
- Boosts hydration by supporting natural hyaluronic acid levels
- Suitable for delicate areas such as the eye contour
Best for
mature skin, ageing skin, dry skin, normal skin, sensitive skin
Where it comes from
sh-Oligopeptide-78 is a synthetic peptide produced through biotechnological fermentation using specially selected yeast strains. It is designed to replicate a specific fragment of a naturally occurring human protein.
Products with sh-Oligopeptide-78
Not every product on UK Lips lists a full ingredient breakdown — so there may be many more formulas that contain sh-Oligopeptide-78 than we can show here. These are the comparisons where we’ve confirmed it in the listed ingredients.