Ingredient guide · H

Hexapeptide-9

Hexapeptide-9 is a synthetic anti-ageing peptide used in skincare to help improve skin firmness and reduce the look of wrinkles. Often described as a collagen-boosting ingredient, it is popular in serums and creams aimed at mature skin. It works gently and is well tolerated by most skin types.

Hexapeptide-9 — Hexapeptide-9 is produced synthetically in laboratories by linking six amino acids in a… | UK Lips ingredient guide

How it works in skincare

In cosmetics Hexapeptide-9 is a lab-crafted peptide designed to mimic part of collagen type I. It signals skin cells to support natural collagen production, helping to reinforce the skin’s structural matrix, improve elasticity and smooth the appearance of fine lines and wrinkles. Formulators like its ability to deliver visible firming results while remaining non-irritating, making it a staple in targeted anti-ageing moisturisers, eye creams and neck treatments sold across the UK.

Key benefits

  • Helps reduce the appearance of fine lines and wrinkles
  • Supports skin firmness and elasticity
  • Improves overall skin texture and smoothness
  • Strengthens the skin’s structural support
  • Enhances the look of tired or sagging skin
  • Suitable for daily use in anti-ageing routines

Best for

mature skin, ageing skin, dry skin, normal skin, sensitive skin

Where it comes from

Hexapeptide-9 is produced synthetically in laboratories by linking six amino acids in a specific sequence. It is not derived from a plant, mineral or animal source but is designed to replicate a fragment of human collagen.

Products with Hexapeptide-9

Not every product on UK Lips lists a full ingredient breakdown — so there may be many more formulas that contain Hexapeptide-9 than we can show here. These are the comparisons where we’ve confirmed it in the listed ingredients.

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