Ingredient guide

Ceramide 1, 3 & 6 II

Ceramides 1, 3 and 6 II are essential lipids naturally found in the skin that act like the mortar between the bricks of your skin barrier. In skincare they are prized for helping to restore and strengthen the skin’s protective layer, locking in moisture and shielding against environmental stress. They are especially popular in UK moisturisers, serums and barrier-repair creams.

Ceramide 1, 3 & 6 II — While naturally present in human skin, the ceramides used in UK skincare are typically … | UK Lips ingredient guide

How it works in skincare

In cosmetics ceramides 1, 3 and 6 II are identical or bio-identical copies of the ceramides found in human skin. They integrate into the intercellular lipid matrix of the stratum corneum, improving barrier cohesion, reducing transepidermal water loss and helping the skin retain softness and suppleness. Formulators often combine the three for optimal barrier support in creams, lotions and targeted treatments.

Key benefits

  • Strengthens the skin barrier
  • Helps lock in moisture
  • Reduces dryness and flaking
  • Improves skin softness and smoothness
  • Supports healthy-looking skin resilience
  • Enhances the performance of other moisturising ingredients

Best for

dry skin, dehydrated skin, sensitive skin, mature skin, compromised skin barrier

Where it comes from

While naturally present in human skin, the ceramides used in UK skincare are typically produced by bio-fermentation of plant oils such as wheat, rice or corn, yielding high-purity, sustainable ingredients suitable for cosmetic use.

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