Ingredient guide

Gluconolactone (5.5%)

Gluconolactone (5.5%) is a gentle, next-generation PHA (polyhydroxy acid) that works as both a mild exfoliant and a powerful humectant. It helps renew the skin’s surface while attracting and holding moisture, making it ideal for those who find traditional AHAs too harsh. At 5.5% it delivers visible smoothing and brightening with minimal irritation.

Gluconolactone (5.5%) — Gluconolactone is naturally derived from the oxidation of glucose, which can be sourced… | UK Lips ingredient guide

How it works in skincare

In skincare and cosmetic formulations, gluconolactone functions as a PHA that gently exfoliates by loosening the bonds between dead skin cells, revealing fresher, smoother skin beneath. Its large molecular size prevents deep penetration, reducing the risk of irritation while still improving skin texture and clarity. It also acts as a humectant and antioxidant, helping to strengthen the skin barrier, bind moisture, and protect against environmental free-radical damage.

Key benefits

  • Gentle exfoliation for smoother skin texture
  • Improves skin radiance and evens tone
  • Strengthens the skin barrier
  • Provides long-lasting hydration
  • Antioxidant protection against free radicals
  • Suitable for daily use with low irritation potential

Best for

sensitive skin, dry skin, mature skin, dehydrated skin, acne-prone skin, rosacea-prone skin

Where it comes from

Gluconolactone is naturally derived from the oxidation of glucose, which can be sourced from corn, rice or other starchy plants.

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